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The Great Stink of Paris and the Nineteenth-Century Struggle against Filth and Germs Eugene W. Straus M.D. shamanism and mysticism and theLate in the summer of 1880, a wave of odors enveloped large portions of Paris. As the stench lingered, outraged residents feared that the foul air would breed an epidemic. Fifteen years later when the City of Light was in the grips of another Great Stink the public conversation about health and disease had changed dramatically. Parisians held their noses and protested, but this time few feared that the odors would spread disease. Historian David S.