If you gain protection from everything, you cant be targeted with a card like Thoughtseize, An Offer You Can't Refuse or Lightning Bolt, and you cant lose life due to damage, either
they could be played at any time but players could only respond to interrupts with other interrupts and could not use instants or activate abilities
In the history of Magic , this has never really happened
Simply generate the sample decklist for the commander you want to compare, import it into Archidekt, and click on the deck comparison button on the upper right hand corner of the deck you want to compare against
Combine Queen of Hearts, Wonderland Empress with the likes of amber cards like Chernabog, Evildoer, Gaston, Baritone Bully and The Queen, Commanding Presence, as well as any villains you fancy from another ink colour, if you choose to put it into your amber deck, and theres some real potential here
There are a number of Walkers too, with tokens and a special legendary artifact that allows for Negan to wield his signature weapon, Lucille